MYCN Oncology FISH

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Synonyms

  • FISH
  • Leukemia FISH
  • Lymphoma FISH

Special Instructions

There will be an additional charge for processing paraffin block samples or for samples that require culture.


Expected Turnaround Time

3 - 5 days



Related Documents


Specimen Requirements


Specimen

Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF), FNA, paraffin block are also acceptable with additional charge.


Volume

Fixed-cell pellet, three slides, 10 mL blood (adult), 5 mL blood (pediatric), or 3 mL bone marrow


Minimum Volume

Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow


Container

Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube


Collection

Transport to the testing lab at room temperature; use a cool pack or LabCorp transport kit. Do not allow sample to freeze.


Storage Instructions

Maintain specimen at room temperature.


Causes for Rejection

Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen


Test Details


Use

Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability)


Methodology

Fluorescence in situ hybridization (FISH)


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
510945 MYCN Oncology FISH 510290 Specimen Type 31208-2
510945 MYCN Oncology FISH 510291 Cells Counted 62361-1
510945 MYCN Oncology FISH 510294 Cells Analyzed 62360-3
510945 MYCN Oncology FISH 510946 FISH Result 48674-6
510945 MYCN Oncology FISH 510296 Interpretation 50398-7
510945 MYCN Oncology FISH 510947 Director Review: 48672-0

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