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SYT Oncology FISH

CPT: Contact CPT coding department at 800-222-7566, ext 6-8400.
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Synonyms

  • FISH
  • Leukemia FISH
  • Lymphoma FISH

Special Instructions

There will be an additional charge for processing paraffin block samples or for samples that require culture.


Expected Turnaround Time

4 - 7 days



Related Documents


Specimen Requirements


Specimen

Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF), FNA, paraffin block are also acceptable with additional charge.


Volume

Fixed-cell pellet, three slides, 10 mL blood (adult), 5 mL blood (pediatric), or 3 mL bone marrow


Minimum Volume

Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow


Container

Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube


Collection

Transport to the testing lab at room temperature; use a cool pack or LabCorp transport kit. Do not allow sample to freeze.


Storage Instructions

Maintain specimen at room temperature.


Causes for Rejection

Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen


Test Details


Use

Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability)


Methodology

Fluorescence in situ hybridization (FISH)


Additional Information

SYT gene rearrangement is most often linked with a t(X;18) chromosome translocation commonly associated with synovial sarcoma.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
510384 SYT Oncology FISH 510260 Specimen Type 31208-2
510384 SYT Oncology FISH 510261 Cells Counted n/a
510384 SYT Oncology FISH 510265 Cells Analyzed n/a
510384 SYT Oncology FISH 510382 FISH Result 48674-6
510384 SYT Oncology FISH 510268 Interpretation 50398-7
510384 SYT Oncology FISH 510383 Director Review: 48672-0

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf