CPT: 82160
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Special Instructions

Note: This test is not the same as Androstenedione. (See tests 004705 and 500152.)

Expected Turnaround Time

8 - 12 days

Specimen Requirements


Serum (preferred) or EDTA plasma, frozen


1 mL

Minimum Volume

0.4 mL (Note: This volume does not allow for repeat testing.)


Red-top tube (Do not use gel-barrier tube.) or lavender-top (EDTA) tube


Centrifuge and separate serum or plasma immediately. Freeze. Send serum or plasma in a plastic transport tube

Storage Instructions


Stability Requirements



Room temperature

9 hours


7 days


7 days

Freeze/thaw cycles

Stable x6

Causes for Rejection

Sample received thawed; gross hemolysis

Test Details


Androsterone is a major metabolite of testosterone and androstenedione along with the enantiomer etiocholanolone. Androsterone is also part of the "backdoor pathway" from allopregnanolone to dihydrotestosterone, which has importance in certain disease states. Androsterone is one of a few steroids with neutral activity that interact with γ-aminobutyric acid (GABA) receptors.


Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by LabCorp. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.


High-pressure liquid chromatography (HPLC)/tandem mass spectrometry (MS-MS)


Kaminski RM, Marini H, Kim WJ, Rogawski MA. Anticonvulsant activity of androsterone and etiocholanolone. Epilepsia. 2005 Jun; 46(6):819-827. 15946323


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
504005 Androsterone, Serum, LCMS 1856-4 504006 Androsterone, Serum, LCMS ng/dL 1856-4

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