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Engraftment Monitoring, Pre

CPT: 81265
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  • Chimerism Testing
  • Preëngraftment Monitoring

Test Includes

Genetic markers to determine if the donor and host samples can be distinguished

Special Instructions

To schedule this test, you must telephone 800-533-1037, HLA customer service.

Expected Turnaround Time

3 - 7 days

Related Documents

For more information, please view the literature below.

Transplant Engraftment Monitoring (Chimerism Testing)

Specimen Requirements


Whole blood or LabCorp buccal swab kit (buccal swab collection kit contains instructions for use of a buccal swab)


Adult tube or LabCorp buccal swab kit

Minimum Volume

3 mL or four buccal swabs


Lavender-top (EDTA) tube, yellow-top (ACD) tube, or Labcorp buccal swab kit. When submitting buccal swabs, please telephone 800-533-1037.

Storage Instructions

Maintain whole blood at room temperature. Keep buccal swabs dry and at room temperature.

Causes for Rejection

Hemolysis; clotted specimen

Test Details


Determine if the potential donor and host have genetic differences that can be used to monitor the acceptance of a stem cell transplant


Identical (monozygotic) twins will have identical alleles and, therefore, host and donor will not be distinguishable. Note: If determination of twin zygosity (monozygotic versus dizygotic) is needed, telephone 800-533-1037, HLA customer service.


DNA analysis by polymerase chain reaction (PCR) of short tandem repeats (STR)


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
168138 Pre Tp Engraft n/a 168138 Pre Tp Engraft n/a

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