Endomysial Antibody, IgA

CPT: 86231
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Expected Turnaround Time

2 - 4 days



Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Storage Instructions

Refrigerate


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Lipemia; hemolysis; microbially-contaminated sera


Test Details


Use

Tissue transglutaminase is the autoantigen recognized by endomysial antibody in celiac disease.1


Methodology

Indirect fluorescent antibody (IFA)


Footnotes

1. Dieterich W, Ehnis T, Bauer M, et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med. 1997 Jul; 3(7):797-801.9212111

References

Biagi F, Pezzimenti D, Campanella J, Vadacca GB, Corazza GR. Endomysial and tissue transglutaminase antibodies in coeliac sera: A comparison not influenced by previous serological testing. Scand J Gastroenterol. 2001 Sep; 36(9):955-958.11521986
National Institute of Health Consensus Development Conference Statement on Celiac Disease. NIH Consens State Sci Statements. 2004 Jun 28-30; 21(1):1-23.17308551

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
164996 Endomysial Antibody IgA 10362-2 164997 Endomysial Antibody IgA 10362-2

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