Anti-CCP (Cyclic Citrullinated Peptide) Antibodies, IgG and IgA, ELISA

CPT: 86200
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Synonyms

  • Anti-CCP
  • Anti-citrullinated protein antibodies (ACPA)
  • Anti-Cyclic Citrullinated Peptide Ab
  • Cyclic Citrullinated Peptide Antibody

Expected Turnaround Time

2 - 3 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Collection

Following collection, serum should be separated from the clot.


Storage Instructions

Room temperature


Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination; addition of azide or other preservative; heat inactivation


Test Details


Use

The presence of CCP antibodies, when considered in conjunction with other laboratory and clinical findings, is an aid in the diagnosis of rheumatoid arthritis (RA). Approximately 70% of RA patients are positive for anti-CCP IgG, while only 2% of random blood donors and control subjects are positive.


Methodology

Enzyme-linked immunosorbent assay (ELISA)


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
164914 Anti-CCP Ab, IgG/IgA 57093-7 164915 Anti-CCP Ab, IgG/IgA units 57093-7

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