Anti-CCP (Cyclic Citrullinated Peptide) Antibodies, IgG and IgA, ELISA

CPT: 86200
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  • Anti-CCP
  • Anti-citrullinated protein antibodies (ACPA)
  • Anti-Cyclic Citrullinated Peptide Ab
  • Cyclic Citrullinated Peptide Antibody

Expected Turnaround Time

2 - 3 days

Specimen Requirements




1 mL

Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Red-top tube or gel-barrier tube


Following collection, serum should be separated from the clot.

Storage Instructions

Room temperature

Stability Requirements



Room temperature

7 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination; addition of azide or other preservative; heat inactivation

Test Details


The presence of CCP antibodies, when considered in conjunction with other laboratory and clinical findings, is an aid in the diagnosis of rheumatoid arthritis (RA). Approximately 70% of RA patients are positive for anti-CCP IgG, while only 2% of random blood donors and control subjects are positive.


Enzyme-linked immunosorbent assay (ELISA)


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
164914 Anti-CCP Ab, IgG/IgA 57093-7 164915 Anti-CCP Ab, IgG/IgA units 57093-7

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