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Human T-Cell Lymphotropic Virus 1, 2 (HTLV-1/HTLV-2) Antibodies, Preliminary Test With Confirmation

CPT: 86790
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Expected Turnaround Time

1 - 4 days

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Specimen Requirements


Serum or plasma


2 mL

Minimum Volume

1.5 mL


Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube


Centrifuge sample to separate serum or plasma. For non−gel-barrier tubes, transfer serum or plasma to a plastic transport tube.

Storage Instructions

Refrigerate. Stable refrigerated for 14 days or frozen for six months.

Causes for Rejection

Gross bacterial contamination; hemolysis; lipemia

Test Details


Screen patients for infection with human T-lymphotropic virus and, if positive, confirm infection with either HTLV-1 or HTLV-2


HTLV-1 or HTLV-2 immunoblot testing should only be performed on patient specimens previously found positive for HTLV infection by immunoassay (EIA).


Chemiluminescent immunoassay (CLIA); line blot (immunoblot)

Reference Interval



Lee H, Swanson P, Shorty VS, Zack JA, Rosenblatt JD, Chen IS. High rate of HTLV-II infection in seropositive drug abusers in New Orleans. Science. 1989 Apr 28; 244(4903):471-475. 2655084
Manns A, Blattner WA. The epidemiology of the human T-cell lymphotropic virus type I and type II: Etiologic role in human disease. Transfusion. 1991 Jan; 31(1):67-75 (review). 1986467
Wong-Staal F, Gallo RC. Human T-lymphotropic retroviruses. Nature. 1985 Oct 3-9; 317(6036):395-403. 2413364
Yoshida M. Human leukemia virus associated with adult T-cell leukemia. Gan. 1983 Dec; 74(6):777-789. 6321284


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
164277 HTLV-I/II Antibodies, Qual. 29901-6 164278 HTLV-I/II Antibodies, Qual 29901-6
Reflex Table for HTLV-I/II Antibodies, Qual
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 164133 HTLV-I/II Immunoblot 164130 HTLV-I IB 6432-9
Reflex Table for HTLV-I/II Antibodies, Qual
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 164133 HTLV-I/II Immunoblot 164132 HTLV-II IB 26656-9

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