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Postejaculatory Urine Microscopic Examination for Sperm

CPT: 81015
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Expected Turnaround Time

2 - 4 days

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Specimen Requirements


Urine (male only)


10 mL

Minimum Volume

2 mL


Sterile urine cup or BD urine transport tube


Immediately after ejaculation, patient should cleanse the penis with water to remove residual semen. Patient should collect urine in clean plastic or glass jar. Care must be taken to include the entire specimen.

Storage Instructions


Causes for Rejection

Specimen more than 48 hours old when unpreserved/refrigerated or more than 72 hours old for BD transport tube; female specimen; samples tested on the IRIS prior to analysis

Test Details


Diagnosis is based on the absence of sperm in the antegrade ejaculate and the presence of sperm in postmasturbatory urine. Retrograde ejaculation may be suspected whenever the semen volume is less than 1 mL. To diagnose retrograde ejaculation, it is necessary to evaluate urine after an ejaculation.

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Visual and microscopic

Additional Information

In males, retrograde ejaculation occurs when the ejaculated fluid, which would normally exit via the urethra, is redirected towards the urinary bladder. Normally, the bladder sphincter contracts and the ejaculate fluid passes through the urethra towards the area of least pressure. In retrograde ejaculation, this sphincter does not function properly. Retrograde ejaculation has multiple causes, including surgical (transurethral resection of the prostate), medication (eg, tamsulosin), complications of diabetes, and in male infertility.


Merck Manuals − online: Infertility Solutions, P.C.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
133116 Postejaculatory Urine Micro 013129 Sperm 8248-7
133116 Postejaculatory Urine Micro 013132 Sperm, Semi-Quant /hpf 49111-8
133116 Postejaculatory Urine Micro 013130 Urine-Color 5778-6
133116 Postejaculatory Urine Micro 013131 Appearance 5767-9

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