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PrEP Use Only: Human Immunodeficiency Virus 1 & 2 (HIV-1/HIV-2), Qualitative, RNA

CPT 87535; 87538
Synonyms
  • HIV
  • PrEP
  • Prophylaxis

Test Details

Methodology

RT-PCR

Result Turnaround Time

2 - 5 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Use

PrEP use only: This test is intended for patients being evaluated for pre-exposure prophylaxis (PrEP) regimens as an aid in the diagnosis of HIV-1 or HIV-2 infection, including acute or primary infection. Presence of HIV-1 or HIV-2 RNA in the plasma of patients without antibodies to HIV-1 or HIV-2 is indicative of acute or primary HIV-1 or HIV-2 infection. This assay may also be used as an additional test, when it is reactive, to confirm HIV-1 infection in an individual whose specimen is repeatedly reactive for HIV-1 and/or HIV-2 antibodies. This assay is not intended for use in donor testing.

Special Instructions

PrEP use only. Contains CPT code modifier for CARES Act.

Specimen Requirements

Specimen

Plasma or serum

Volume

1 mL

Minimum Volume

650 μL (Note: This volume does not allow for repeat testing.)

Container

Lavender-top (EDTA) tube, BD SST tube or BD Vacutainer PPT plasma preparation tube

Collection Instructions

Collect specimen in lavender-top (EDTA), gel-barrier (SST tube) or a PPT plasma preparation tube. Specimens require centrifugation within 24 hours of collection. Transfer serum or plasma to a polypropylene screw-cap tube for shipment. Ship frozen.

Stability Requirements

Temperature

Period

Refrigerated

7 days

Frozen

6 weeks

Freeze/thaw cycles

Stable x3

Note: Stability provided by manufacturer or literature reference.

Storage Instructions

Freeze (preferred) or refrigerate.

Causes for Rejection

Specimen grossly hemolyzed; room temperature specimen received

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
083973 PrEP: HIV-1/HIV-2 Qual, NAA 96557-4 139826 HIV-1 RNA 25835-0
083973 PrEP: HIV-1/HIV-2 Qual, NAA 96557-4 139827 HIV-2 RNA 69353-1
Order Code083973
Order Code NamePrEP: HIV-1/HIV-2 Qual, NAA
Order Loinc96557-4
Result Code139826
Result Code NameHIV-1 RNA
UofM
Result LOINC25835-0
Order Code083973
Order Code NamePrEP: HIV-1/HIV-2 Qual, NAA
Order Loinc96557-4
Result Code139827
Result Code NameHIV-2 RNA
UofM
Result LOINC69353-1