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Labcorp.com

Cobalt, Urine

CPT: 82570; 83018
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Test Includes

Cobalt, urine; creatinine, urine; cobalt:creatinine ratio


Special Instructions

Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.


Expected Turnaround Time

2 - 4 days


Related Information


Related Documents


Specimen Requirements


Specimen

Urine (random or 24-hour)


Volume

5 mL


Minimum Volume

1.5 mL


Container

Plastic urine container, no preservative


Collection

Sampling time is end of shift at end of work week. Metals with timing “end of shift at end of work week” (meaning four or five consecutive working days with exposure) are eliminated with half-lives longer than five hours. Such metals accumulate in the body during the work week; therefore, their timing is critical in relation to previous exposures.

Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.


Storage Instructions

Maintain specimen at room temperature.


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Test Details


Use

Monitor industrial exposure to cobalt


Limitations

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Methodology

Inductively-coupled plasma/mass spectrometry (ICP/MS)


Reference Interval

Environmental exposure: 1.0−2.0 μg/L; <2.0 μg/g creatinine

Occupational exposure: BEI® (sampling time is end of shift at end of work week): 15.0 μg/L1


Footnotes

1. TLVs and BEIs, Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices 2010, American Conference of Governmental Industrial Hygienists (ACGIH).

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
071514 Cobalt, Urine 071515 Cobalt, Urine ug/L 5628-3
071514 Cobalt, Urine 071517 Cobalt, Urine 24 Hr ug/24 hr 29916-4
071514 Cobalt, Urine 723280 Creatinine(Crt),U g/L 2161-8
071514 Cobalt, Urine 071518 Cobalt/Creat. Ratio ug/g creat 13468-4

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