Cobalt, urine; creatinine, urine; cobalt:creatinine ratio
Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Urine (random or 24-hour)
Plastic urine container, no preservative
Sampling time is end of shift at end of work week. Metals with timing “end of shift at end of work week” (meaning four or five consecutive working days with exposure) are eliminated with half-lives longer than five hours. Such metals accumulate in the body during the work week; therefore, their timing is critical in relation to previous exposures.
Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.
Maintain specimen at room temperature.
Monitor industrial exposure to cobalt
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Inductively-coupled plasma/mass spectrometry (ICP/MS)
• Environmental exposure: 1.0−2.0 μg/L; <2.0 μg/g creatinine
• Occupational exposure: BEI® (sampling time is end of shift at end of work week): 15.0 μg/L1
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|071514||Cobalt, Urine||071515||Cobalt, Urine||ug/L||5628-3|
|071514||Cobalt, Urine||071517||Cobalt, Urine 24 Hr||ug/24 hr||29916-4|
|071514||Cobalt, Urine||071518||Cobalt/Creat. Ratio||ug/g creat||13468-4|
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