Vancomycin, Serum, Trough

CPT: 80202
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  • Vancocin®

Special Instructions

Peak levels should be ordered using Test No. 070327. Trough levels should be ordered using Test No. 070328. Please label tubes appropriately as “peak” and “trough.”

Expected Turnaround Time

Within 1 day

Related Documents

Specimen Requirements


Serum or plasma


1 mL

Minimum Volume

0.3 mL


Red-top tube, lavender-top (K2- or K3- EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.


Transfer separated serum or plasma to a plastic transport tube. Trough concentrations should be monitored. The trough sample is drawn immediately prior to the next dose.

Storage Instructions


Stability Requirements



Room temperature

3 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Gel-barrier tube; hemolysis; lipemia; gross bacterial contamination

Test Details


Monitor therapeutic drug level




AMA Division of Drugs and Toxicology, Drug Evaluations Subscription, Chicago, IL: American Medical Association, Spring 1990.
Brunton L, Lazo J, Parker K. Goodman & Gillman's The Pharmacological Basis of Therapeutics. 11th ed. New York, NY: McGraw-Hill, 2006.
Burtis CA, Ashwood CR, Bruns DE. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. St Louis, MO: Elsevier Saunders, 2006.
Dart RC, Caravati EM, McGuigan MA, et al. Medical Toxicology. Philadelphia, PA: Lippincott Williams & Wilkins, 2006.
Mosby's Drug Consult. 17th ed. St Louis, MO: Elsevier Saunders, 2007.
Rybak M, Lomaestro B, Rotschafer JC, et al. Therapeutic Monitoring of Vancomycin in Adult Patients: A consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists. Am J Health Syst Pharm. 2009 Jan 1;(66)(1)82-98.19106348


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
070328 Vancomycin Trough, Serum 4092-3 070338 Vancomycin Trough, Serum ug/mL 4092-3

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