Glutathione, Total

CPT: 82978
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Expected Turnaround Time

4 - 7 days

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Specimen Requirements


Whole blood


500 μL

Minimum Volume

100 μL


Yellow-top ACD-B tube (acid citrate dextrose) or yellow-top ACD-A tube


Allow ACD tubes to fill completely; gently invert 8 to 10 times.

Storage Instructions

Room temperature

Stability Requirements



Room temperature

14 days


14 days


7 days

Causes for Rejection

Blood collected in tubes other than ACD tubes; ACD collection tubes inadequately filled; hemolyzed specimens; clotted specimens

Test Details


Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as preëclampsia.


Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by LabCorp. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.


Liquid chromatography/tandem mass spectrometry (LC/MS-MS)


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
007700 Total Glutathione 91685-8 007701 Total Glutathione ug/mL 2383-8

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