Cytomegalovirus (CMV) Antibodies, IgG

CPT: 86644
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Special Instructions

Identify specimen as acute or convalescent. Acute and convalescent specimens must be submitted on separate test request forms.

Expected Turnaround Time

1 - 2 days

Related Documents

Specimen Requirements




0.5 mL

Minimum Volume

0.2 mL (Note: This volume does not allow for repeat testing.)


Red-top tube or gel-barrier tube

Storage Instructions


Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x4

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination

Test Details


Aid in the determination of serological status to CMV. IgG antibodies rise gradually and persist for the rest of an individual's life. The specific IgG assay is useful in distinguishing who has been exposed to the virus from those who have not. Levels of IgM to hCMV usually increase for some weeks and decrease slowly thereafter, in four to six months. Occasionally, IgM may circulate for years. For the IgM assay, see Cytomegalovirus (CMV) Antibodies, Quantitative, IgM [096727].


Most adults are infected with CMV and it is normal to be a carrier of the virus.


Chemiluminescent immunoassay (CLIA)

Reference Interval

• Negative: <0.60 U/mL

• Equivocal: 0.60−0.69 U/mL

• Positive: >0.69 U/mL

Additional Information

CMV causes an infectious mononucleosis syndrome clinically indistinguishable from heterophil positive mononucleosis. Signs include fever, malaise, and increased transaminase levels without jaundice.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
006494 Cytomegalovirus (CMV) Ab, IgG 5124-3 006499 Cytomegalovirus (CMV) Ab, IgG U/mL 5124-3

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