Syphilis: RPR With Reflex to RPR Titer

CPT: 86592
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  • Nontreponemal
  • Rapid Plasma Reagin
  • RPR

Expected Turnaround Time

Within 1 day

Related Documents

Specimen Requirements




1 mL

Minimum Volume

0.5 mL


Red-top tube or gel-barrier tube

Storage Instructions

Room temperature

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination; plasma specimen

Test Details


This test can be used to follow treatment response in patients being treated for syphilis infection. This assay should not be used to screen for syphilis infection. To screen for syphilis infection, a reflex cascade that includes both RPR and a treponema-specfic assay should be utilized, such as Treponema pallidum (Syphilis) Screening Cascade [082345] or Rapid Plasma Reagin (RPR) Test With Reflex to Quantitative RPR and Confirmatory Treponema pallidum Antibodies [012005]. See Related Information to view these tests.


Charcoal flocculation

Reference Interval



Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
006072 RPR 20507-0 006072 RPR 20507-0
Reflex Table for RPR
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 006464 RPR, Quant. 006464 RPR, Quant. titer 31147-2

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