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Estrogens, Total

CPT: 82672
Updated on 08/3/2021
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Expected Turnaround Time

1 - 4 days

2 - 4 days

1 - 4 days


Related Documents


Specimen Requirements


Specimen

Serum

Serum or plasma

Serum


Volume

0.8 mL


Minimum Volume

0.5 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube

Red-top tube, gel-barrier tube, or green-top (heparin) tube

Red-top tube or gel-barrier tube


Collection

If tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube.

If tube other than a gel-barrier tube is used, transfer separated serum or plasma to a plastic transport tube.

If tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube. to a plastic transport tube.


Storage Instructions

Room temperature

Refrigerate

Room temperature


Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Temperature

Period

Room temperature

3 days

Refrigerated

7 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Gross hemolysis; gross lipemia; icteric specimen

Gross hemolysis; recent isotopic scan; gross lipemia; icteric specimen

Gross hemolysis; gross lipemia; icteric specimen; gross lipemia; icteric specimen


Test Details


Use

Evaluate for ovarian estrogen producing tumor in the premenarcheal and postmenopausal female; evaluate estrogen excess in males. Estrogen analysis may be helpful in establishing time of ovulation and optimal time for conception. Serial samples must be collected over several days to evaluate baseline and peak total estrogen levels.


Methodology

Enzyme-linked immunoassay (ELISA)

Radioimmunoassay (RIA)

Enzyme-linked immunoassay (ELISA)


Reference Interval

See table.1

Age

Male (pg/mL)

Female (pg/mL)

Prepubertal

<40

<40

Adults

56−213

Female Cycle:

1 to 10 d: 16−328

11 to 20 d: 34−501

21 to 30 d: 48–350

Post-menopausal: 40–244

See table.1

Age

Male (pg/mL)

Female (pg/mL)

Prepubertal

<40

<40

Adults

40−115

Female cycle:

Castrate: <40

1 to 10 d: 61−394

11 to 20 d: 122−437

21 to 30 d: 156−350

Postmenopausal: <40

HMG treatment for ovulation induction: 400−800

Tanner Stage

I

10−38

10−46

II

17−45

22−63

III

22−55

24−110

IV

27−80

40−180

V

25−80

60−280

See table.1

Age

Male (pg/mL)

Female (pg/mL)

Prepubertal

<40

<40

Adults

56−213

Female Cycle:

1 to 10 d: 16−328

11 to 20 d: 34−501

21 to 30 d: 48–350

Post-menopausal: 40–244


Footnotes

1. Tietz NW, ed. Clinical Guide to Laboratory Tests. 3rd ed. Philadelphia, Pa: WB Saunders Co;1995:220.

References

Ashby CD, Danzer HC, Swerdloff RS, et al. Estrogen radioimmunoassay suitable for the monitoring of ovulation induction. Clin Chem. 1980; 26(8):1143-1146. 7389084
Marshall JR. Induction of ovulation. Clin Obstet Gynecol. 1978; 21(1):147-162 (review). 343954
Taymor ML, Yussman MA, Gminski D, et al. Estrogen monitoring in ovulation induction. Fertil Steril. 1970; 21(11):759-762.5474219

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
004549 Estrogens, Total 2254-1 004549 Estrogens, Total pg/mL 2254-1

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