VDRL, Cerebrospinal Fluid

CPT: 86592
Print Share

Test Details

Synonyms

  • CSF Venereal Disease Research Laboratory (VDRL) Test

Use

Test for syphilis, neurosyphilis

Methodology

Agglutination

Reference Interval

Nonreactive

Additional Information

A positive VDRL in a spinal fluid uncontaminated by serum is essentially diagnostic of neurosyphilis; however, a negative test may occur in 30% of patients with tabes dorsalis. The CSF VDRL may take years to become nonreactive after adequate therapy. In AIDS patients, serial CSF VDRL determinations may be needed when neurosyphilis is suspected. By requiring either a positive plasma RPR or FTA-ABS, seropositivity of CSF VDRL could increase to 90%.

Specimen Requirements

Specimen

Cerebrospinal fluid (CSF)

Volume

1 mL

Minimum Volume

0.5 mL

Container

Sterile tube

Storage Instructions

Refrigerate

Causes for Rejection

Hemolysis; gross bacterial contamination

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
006445 VDRL, CSF 22459-2 006445 VDRL, CSF 22459-2

For Providers

Please login to order a test.

 

© 2017  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf