Organic Acid Analysis, Urine

CPT: 83919
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Test Details

Use

Urine organic acid testing is useful in the diagnosis and monitoring of patients with inborn errors of organic acid metabolism, inborn errors of amino acid metabolism, urea cycle defects, and defects of the mitochondrial respiratory chain.

Limitations

Organic acid analysis may fail to detect certain disorders that are characterized by minimal or intermittent metabolite excretion.

Methodology

Gas chromatography/mass spectrometry (GC/MS)

Specimen Requirements

Specimen

Urine (random), frozen

Volume

10 mL

Minimum Volume

3 mL

Container

Plastic urine container, no preservative

Storage Instructions

Freeze

Stability Requirements

Temperature

Period

Frozen

12 months

Causes for Rejection

Urine too dilute; quantity not sufficient for analysis

Clinical Information

References

Shapira E, Blitzer MG, Miller JB, et al. Biochemical Genetics: A Laboratory Manual. New York, NY: Oxford University Press;1989.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
716720 Organic Acid Analysis, Urine 716721 Organic Acid Interpretation 49287-6
716720 Organic Acid Analysis, Urine 716723 Contact: N/A
716720 Organic Acid Analysis, Urine 716722 Methodology: 49549-9
Reflex Table for Methodology:
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 700480 Disclaimer: 700480 Disclaimer: N/A

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