Iodine, 24-Hour Urine

CPT: 83789
Print Share

Test Details


Monitor exposure to iodine; evaluate for iodine deficiency disorders (IDDs), excessive iodine intake, or iodine in the workplace

IDDS by Age Group

Age Groups

Health Consequences of Iodine Deficiency

Zimmerman MB, "Iodine Deficiency," Endocrine Reviews, The Endocrine Society, 2009, 30:376-408.

All ages


Increased susceptibility of thyroid gland to nuclear radiation




Congenital anomalies

Perinatal mortality


Infant mortality

Endemic cretinism

Children and adolescents

Impaired mental function

Delayed physical development


Impaired mental function

Reduced work productivity

Toxic nodular goiter; iodine-induced hyperthyroidism

Increased occurrence of hypothyroidism in moderate-to-severe iodine deficiency; decreased occurrence of hypothyroidism in mild-to-moderate iodine deficiency

Other forms of thyroid problems, namely iodine-induced hypothyroidism, autoimmune thyroiditis, and hyperthyroidism associated with excessive iodine intake, have become a greater concern than deficiency disorders.1


Inductively-coupled plasma/mass spectrometry (ICP/MS)

Reference Interval

100.0−460.0 μg/24 hours

Specimen Requirements


Urine (24-hour)


5 mL

Minimum Volume

2 mL


Plastic urine container, no preservative


Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Transport the specimen promptly to the laboratory. Container must be labeled with the patient's full name, room number, the date and time collection started, and the date and time collection finished. Do not use preservative.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Clinical Information

Special Instructions

If 24-hour urine is submitted, the test request form must state 24-hour collection volume.


1. Hollowell JG, Staehling NW, Hannon WH, et al. Iodine nutrition in the United States, trends and public health implications: Iodine excretion data from National Health and Nutrition Examination Surveys I and III (1971-1974 and 1988-1994). J Clin Endocrinol Metab. 1998; 83(10):3401-3408.9768638


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
070222 Iodine, 24 Hr Urine 070164 Iodine, Urine ug/L 2495-0
070222 Iodine, 24 Hr Urine 070223 Iodine, 24 Hr Urine ug/24 hr 2492-7

For Providers

Please login to order a test.


© 2018  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at Additional information regarding LOINC® codes can be found at, including the LOINC Manual, which can be downloaded at