HLA DR1/3/4/5, DQ Intermediate Resolution

CPT: 81375
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Special Instructions

If you have questions, please call 800-533-1037 (HLA customer service) for assistance in selecting the proper HLA test for the patient.


Expected Turnaround Time

3 - 7 days


Related Documents


Specimen Requirements


Specimen

Whole blood or buccal swabs


Volume

7 mL whole blood or four buccal swabs


Minimum Volume

3 mL whole blood or four buccal swabs


Container

Lavender-top (EDTA) tube or four buccal swabs in a sealed envelope (buccal swab kit). When submitting buccal swabs, please use a buccal swab kit provided by LabCorp. To obtain the buccal swab kit, please telephone 800-533-1037.


Storage Instructions

Maintain specimen at room temperature; protect from extreme heat or cold. Do not freeze.


Causes for Rejection

Hemolyzed specimen; clotted specimen; wrong specimen container


Test Details


Use

HLA antigens may be correlated with certain disease states or other clinical conditions. Indicate in clinical information which antigen(s) is of interest. Also used for screening of transplant candidates and potential donors, transfusion of specifically compatible blood products, among others.


Limitations

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Methodology

Sequence-based typing (SBT), sequence oligonucleotide probes (SSOP), and/or sequence-specific primers (SSP) as needed to obtain the required resolution.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
167120 HLA DRB1,3,4,5,DQB1 (IR) 166215 DRB1 57298-2
167120 HLA DRB1,3,4,5,DQB1 (IR) 166223 DRB1 57298-2
167120 HLA DRB1,3,4,5,DQB1 (IR) 166226 DRB3 59022-4
167120 HLA DRB1,3,4,5,DQB1 (IR) 166229 DRB3 59022-4
167120 HLA DRB1,3,4,5,DQB1 (IR) 166227 DRB4 59021-6
167120 HLA DRB1,3,4,5,DQB1 (IR) 166230 DRB4 59021-6
167120 HLA DRB1,3,4,5,DQB1 (IR) 166228 DRB5 59020-8
167120 HLA DRB1,3,4,5,DQB1 (IR) 166232 DRB5 59020-8
167120 HLA DRB1,3,4,5,DQB1 (IR) 168011 DQB1 Allele 1 53938-7
167120 HLA DRB1,3,4,5,DQB1 (IR) 168020 DQB1 Allele 2 53938-7
167120 HLA DRB1,3,4,5,DQB1 (IR) 167384 HLA Methodology 49549-9

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf