Chromosome Analysis, Lymph Node

TEST: 511485
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CPT: Contact CPT coding department at 800-222-7566, ext 6-8400.
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Synonyms

  • Lymphoma Karyotyping

Special Instructions

Indicate tentative diagnosis on the test request form. This is necessary for proper culturing and result interpretation.

Please do not submit hypocellular fine-needle aspirates (FNAs) for chromosomal analysis. Target FISH analysis is recommended for hypocellular FNAs. Please direct any questions regarding this test to oncology customer service at 800-345-4363.

Expected Turnaround Time

7 - 10 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Specimen Requirements

Specimen

Lymph node

Volume

0.5 to 1 cm³ tissue

Container

Lymph node in Lymph Node Transport bottle.

Collection

Submit lymph node at room temperature using Lymph Node Transport Kit (supplied by Roche). Specimens should arrive in the laboratory within 48 hours of collection. Indicate date and time of collection on the test request form.

Storage Instructions

Maintain specimen at room temperature.

Patient Preparation

Patient should not be on chemotherapy.

Causes for Rejection

Gross contamination

Test Details

Use

Identify specific chromosomal abnormalities associated with non-Hodgkin's lymphoma

Limitations

FNAs are frequently unsuccessful. Please see Special Instructions. Normal lymph nodes are often nonmitotic, providing no results.

Methodology

Short-term cell culture; chromosome harvest; G-banding; analysis (20 metaphases) and karyotyping

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
511485 Chromosome Analysis,Lymph Node 511521 Specimen Type 31208-2
511485 Chromosome Analysis,Lymph Node 511522 Cells Counted 62361-1
511485 Chromosome Analysis,Lymph Node 511523 Cells Analyzed 62360-3
511485 Chromosome Analysis,Lymph Node 511524 Cells Karyotyped 55199-4
511485 Chromosome Analysis,Lymph Node 511525 GTG Band Resolution Achieved 62358-7
511485 Chromosome Analysis,Lymph Node 511526 Cytogenetic Result 62356-1
511485 Chromosome Analysis,Lymph Node 511527 Interpretation 62365-2
511485 Chromosome Analysis,Lymph Node 511528 Director Review: 48672-0
511485 Chromosome Analysis,Lymph Node 512123 PDF 51967-8

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf