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Breast Cancer Prognosis Profile II, Paraffin Block
Estrogen/progesterone receptor (ER/PR) assay; HER-2/CEP17 FISH assay
Provide prognostic information to aid the physician in determining risk of recurrence and potential benefits of therapy options for the breast cancer patient; HER-2/neu gene amplification status is a predictor of response to certain breast cancer treatments, including targeted immunotherapy.
Use of fixatives other than 10% formalin may not yield equivalent or satisfactory results.
ER/PR: immunohistochemistry; HER-2/neu gene amplification status: fluorescence in situ hybridization (FISH)
Formalin-fixed, paraffin-embedded (FFPE) tumor
One paraffin block
Specimen should be fixed in 10% neutral-buffered formalin. Optimum fixation time is 12 to 24 hours, not to exceed 48 hours.
Maintain specimen at room temperature.
Please direct any questions regarding this test to oncology customer service at 800-345-4363.