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Enhanced Detection of ctDNA Molecular Response for Immunotherapy Treated Non-small Cell Lung Cancer Through Analyses of Cell-free and Matched White Blood Cell DNA

07 Apr 2024

In this real-world study of patients with advanced NSCLC treated with immune checkpoint inhibitors, integrated analysis of ctDNA and matched white blood cells measured molecular response through longitudinal liquid biopsy and more accurately predicted radiographic response and overall survival.

Authors:

  • Jennifer B. Jackson
  • James R. White
  • Pedro Rocha
  • Andrew Georgiadis
  • Ellen L. Verner
  • Amy E. Greer
  • Rafael Bach
  • Laura Masfarre Pinto
  • Nil Navarro
  • Alvaro Taus
  • Beatriz Bellosillo Paricio
  • Sergi Clavé
  • Mark Sausen
  • Edurne Arriola