Posters
Comprehensive Genomic and Immune Profiling of Early-Onset Colorectal Cancer
01 Nov 2023
This study investigated 1757 colorectal cancer (CRC) specimens that received comprehensive genomic and immune profiling, and identified that Early-onset CRC (patient age ≤ 50y) had lower tumor mutational burden (TMB) and reduced immunogenicity compared to late-onset CRC (patient age > 50y).
- Laura Vidal
- Kamal S. Saini
- Kyle C. Strickland
- Sarabjot Pabla
- Heidi C. Ko
- Rebecca A. Previs
- Shengle Zhang
- Jeffrey M. Conroy
- Pratheesh Sathyan
- Taylor J. Jensen
- Marcia Eisenberg
- Brian Caveney
- Prasanth Reddy
- Eric A. Severson
- Shakti Ramkissoon