Clinical Laboratory Experience With Prenatal cfDNA Screening in Triplet Pregnancies

Objective

Prenatal cfDNA screening is the most sensitive and specific screen for common aneuploidies in singleton and twin pregnancies and has been endorsed by several professional societies as a first-tier screen or contingent screen. However, data for triplet pregnancies is lacking, as these pregnancies are relatively uncommon and obtaining sufficient data for a robust analysis of test performance is challenging.

Authors

Erica Soster, Brittany Dyr, Samantha Caldwell, Savannah Moore, Eyad Almasri, Hany Magharyous, Juan-Sebastian Saldivar, Phillip Cacheris