Test Details
Methodology
Inductively-coupled plasma/mass spectrometry (ICP/MS)
Result Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Creatinine, urine; nickel, urine; nickel:creatinine ratio; nickel, urine (24-hour)
Use
This test is used to monitor exposure to nickel.
Special Instructions
State 24-hour volume on the request form, if applicable. Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Urine (random or 24-hour)
Volume
5 mL
Minimum Volume
1.5 mL
Container
Plastic urine container, no preservative
Collection Instructions
Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
| Freeze/thaw cycles | Stable x3 |
Reference Range
• Environmental exposure: 0.0−9.9 μg/g creatinine; 0.0−7.0 μg/24 hours
• Occupational exposure (soluble compounds): 30 μg/g creatinine1
Storage Instructions
Maintain specimen at room temperature.
References
Footnotes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 071563 | Nickel, Urine | 071569 | Nickel, Urine | ug/L | 14099-6 | |
| 071563 | Nickel, Urine | 071572 | Nickel, Urine (24hr) | ug/24 hr | 5705-9 | |
| 071563 | Nickel, Urine | 723280 | Creatinine(Crt),U | g/L | 2161-8 | |
| 071563 | Nickel, Urine | 071570 | Nickel/Creat. Ratio | ug/g creat | 13472-6 | |
| Order Code | 071563 | |||||
| Order Code Name | Nickel, Urine | |||||
| Order Loinc | ||||||
| Result Code | 071569 | |||||
| Result Code Name | Nickel, Urine | |||||
| UofM | ug/L | |||||
| Result LOINC | 14099-6 | |||||
| Order Code | 071563 | |||||
| Order Code Name | Nickel, Urine | |||||
| Order Loinc | ||||||
| Result Code | 071572 | |||||
| Result Code Name | Nickel, Urine (24hr) | |||||
| UofM | ug/24 hr | |||||
| Result LOINC | 5705-9 | |||||
| Order Code | 071563 | |||||
| Order Code Name | Nickel, Urine | |||||
| Order Loinc | ||||||
| Result Code | 723280 | |||||
| Result Code Name | Creatinine(Crt),U | |||||
| UofM | g/L | |||||
| Result LOINC | 2161-8 | |||||
| Order Code | 071563 | |||||
| Order Code Name | Nickel, Urine | |||||
| Order Loinc | ||||||
| Result Code | 071570 | |||||
| Result Code Name | Nickel/Creat. Ratio | |||||
| UofM | ug/g creat | |||||
| Result LOINC | 13472-6 |