Helicobacter pylori Stool Antigen      Number 180764 CPT 87338 Related Information Helicobacter pylori Antibodies, IgG Helicobacter pylori Antibodies, IgM Helicobacter pylori Culture Synonyms Campylobacter From Stomach ; Campylobacter pylori ; Culture, Helicobacter pylori ; HpSA Test Includes Immunoassay for Helicobacter pylori Specimen Stool Volume 2 g (thumbnail size portion of stool), 2 mL liquid stool Minimum Volume 1 g stool, 1 mL liquid stool Container Sterile screw-cap vial (ParaPak white clean vial) Storage Instructions Specimen should be stored at 4°C and transported to the laboratory within 24 hours of collection. If a longer period is required, the specimen should be frozen at -70°C or maintained on dry ice. Causes for Rejection Inappropriate specimen transport conditions (eg, room temperature) or device; unlabeled specimen or name discrepancy between specimen and request label; specimen received after prolonged delay (usually more than 72 hours); leaking specimen; specimen received in inappropriate container (denture cup, “Cool Whip” container, margarine container, or similar container) Use Establish the presence and possible etiologic role of Helicobacter pylori in cases of chronic gastric ulcer, gastritis, duodenal ulcer, dyspepsia, etc Methodology Immunoassay Contraindications Antimicrobials, proton pump inhibitors, and bismuth preparations are known to suppress H. pylori, and ingestion of these prior to H. pylori testing may give a false-negative result. If a negative result is obtained for a patient ingesting these compounds within 2 weeks prior to performing the stool antigen test, it may be a false-negative result and the test should be repeated on a new specimen obtained 2 weeks after discontinuing treatment. A positive result for a patient ingesting these compounds within 2 weeks prior to performing the stool antigen test should be considered accurate.

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