Mycobacterium tuberculosis Detection, Nucleic Acid Amplification (NAA)      Number 550087 CPT 87556 Synonyms TB Stat Test Specimen Sputum, respiratory aspirate, lavage fluid, pleural fluid, cerebrospinal fluid, or respiratory tissue Volume 5 mL, 1 mL cerebrospinal fluid (CSF), or a small piece of respiratory tissue (2 mL from needle biopsy) Container Sterile screw-cap container; seal cap tightly. Collection If the specimen is to be split for additional testing, it should be divided so that each portion is transported at the appropriate temperature. Storage Instructions Refrigerate Patient Preparation When collecting sputum, have the patient brush teeth or remove dentures and rinse mouth with water. Instruct the patient not to collect saliva. When collecting aspirates, use standard aseptic preparation. Respiratory tissue specimens may be fresh or frozen. Causes for Rejection Inappropriate specimen transport device; unlabeled specimen or name discrepancy between specimen and request label; specimen received after prolonged delay (usually more than 72 hours). Blood and bone marrow are not suitable for amplification test. Tissue not of respiratory origin will not be tested. Use Detect and identify Mycobacterium tuberculosis in sputum and respiratory specimen Limitations This procedure may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients. Methodology Nucleic acid amplification (NAA) technology, such as polymerase chain reaction, transcription mediate amplification, or strand displacement amplification

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