Paternity Studies
| Paternity Studies | | | |
| Number | | 176529 |
| CPT | | (call client services) |
| Synonyms | | AMPFLP Analysis ; DNA Analysis for Parentage Evaluation ; Exclusion of Parentage ; Genetic Studies ; Genotype, Immigration ; Parentage Studies ; STR Analysis ; Twins (Monozygotic vs Dizygotic) |
| Special Instructions | | Appointments and paternity kits are required. Specimens must be collected with chain-of-custody paper work. Clinical account numbers cannot be used. To receive a complete paternity kit, blood or buccal swab, set up account numbers, or for an appointment, telephone 800-742-3944. |
| Storage Instructions | | Maintain specimen at room temperature and keep dry. |
| Causes for Rejection | | Improper labeling; improperly filled out client authorization/chain-of-custody form; insufficient volume of DNA on the buccal swabs |
| Use | | Determine the chance of paternity or nonpaternity in cases of disputed paternity, establish blood relationship of potential immigrant, possible exchange of infants in nursery, and kidnapped child; provide evidence that twins are monozygotic versus dizygotic |
| Limitations | | Probability of parentage is provided for nonexcluded individuals which is a probability not a “yes” answer. Some tests may be inconclusive. Mutations, related alleged fathers, and other genetic limitations may affect the test. |
| Methodology | | DNA analysis by polymerase chain reaction (PCR) |
| References | | Brooks MA, “Paternity Testing,” Modern Blood Banking and Transfusion Practices, Harmening D, ed, 2nd ed, Philadelphia, PA: FA Davis Co, 1989, 379-89. Bryant NJ, “Paternity Testing: Current Status and Review,” Transfus Med Rev, 1988, 2(1):29-39. “Guidelines for Reporting Estimates of Probability of Paternity,” Council on Scientific Affairs, JAMA, 1985, 253(22):3298. |
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