Antinuclear Antibodies (ANA) With Reflex
Antinuclear Antibodies (ANA) With Reflex
    
Number
164962
CPT
86038
Synonyms
ANA ; Centromere B ; dsDNA ; ENA ; Histone ; Sjögren ; SLE
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination; icterus
Methodology
Multiplex bead flow cytometry
References

Kopnitsky M and Meenan J, “AtheNA Multilyte ANA Test System: The Next Generation of Antinuclear Testing,” Clin Lab Products, 2002, 31:38-49.

Tan EM, Chan EK, Sullivan KF, et al, “Antinuclear Antibodies (ANAs): Diagnostically Specific Immune Markers and Clues Toward the Understanding of Systemic Autoimmunity,” Clin Immunol Immunopathol, 1988, 47(2):121-41.

von Muhlen CA and Nakamura RM, “Clinical and Laboratory Evaluation of Systemic Rheumatic Diseases,” Clinical Diagnosis and Management by Laboratory Methods, 20th ed, Henry JB, ed, Philadelphia PA: WB Sanders Co, 2001, 974-89.

von Muhlen CA, Tan EM, “Autoantibodies in the Diagnosis of Systemic Rheumatic Diseases,” Semin Arthritis Rheum, 1995, 24(5):323-58.


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