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MyoMarker® 3 Profile (RDL)

CPT: 83516(x9); 86235(x7)
83516(x8); 83520; 86235(x7)
83516(x9); 86235(x7)
Updated on 10/6/2021
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  • Myomarker 3
  • Myositis
  • Myositis Panel 3

Test Includes

Anti-PM/Sci-100 Ab; Anti-MDA5 Ab (CADM-140); Anti-NXP-2 Ab; Anti-TIF-1 gamma Ab; Anti-SRP Ab; Anti-U3 RNP (Fibrillarin Ab); Anti-U2 RNP Ab; Anti-Mi-2 Ab; Anti-PL-7 Ab; Anti-PL-12 Ab; Anti-EJ Ab; Anti-OJ Ab; Anti-Ku Ab; Anti-Jo-1 Ab; Anti-U1 RNP Ab; Anti-SS-A 52kD Ab, IgG

Expected Turnaround Time

14 - 21 days

14 - 21 days

14 - 21 days

14 - 21 days

14 - 21 days

Related Documents

Specimen Requirements




5 mL

Minimum Volume

4 mL (Note: This volume does not allow for repeat testing.)


Red-top tube or gel-barrier tube


Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.

Storage Instructions


Stability Requirements



Room temperature

7 days


14 days


60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

Test Details


The idiopathic inflammatory myopathies (IIM) are a hetergeneous group of disorders characterized by muscle weakness, resulting from chronic muscle inflammation of unknown cause. Patients with IIM have a variety of autoantibodies with various clinical utilities that fall into two main groups. One group of autoantibodies are found in patients with myositis and are known as Myositis Specific Autoantibodies (MSA). The MSAs are highly specific for patients with polymyositis (PM) dermatmyositis (DM), anti-synthetase syndrome and necrotizing myositis. The second group of autoantibodies are considered Myositis Associated Autoantibodies (MAA). These appear in myositis overlap syndrome and in other connective tissue diseases, which correlate with certain clinical and/or pathophysiological conditions.


This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Enzyme-linked immunosorbent assay (ELISA); RIPA Gel Radiography


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520080 MyoMarker 3 Profile (RDL) 520259 Anti-Jo-1 Ab (RDL) Units 35333-4
520080 MyoMarker 3 Profile (RDL) 520046 Anti-PL-7 Ab (RDL) 33772-5
520080 MyoMarker 3 Profile (RDL) 520049 Anti-PL-12 Ab (RDL) 33771-7
520080 MyoMarker 3 Profile (RDL) 520027 Anti-EJ Ab (RDL) 45149-2
520080 MyoMarker 3 Profile (RDL) 520029 Anti-OJ Ab (RDL) 45152-6
520080 MyoMarker 3 Profile (RDL) 520040 Anti-SRP Ab (RDL) 33921-8
520080 MyoMarker 3 Profile (RDL) 520001 Anti-Mi-2 Ab (RDL) 18485-3
520080 MyoMarker 3 Profile (RDL) 520252 Anti-TIF-1gamma Ab (RDL) Units 88739-8
520080 MyoMarker 3 Profile (RDL) 520251 Anti-MDA-5 Ab (CADM-140)(RDL) Units 88725-7
520080 MyoMarker 3 Profile (RDL) 520250 Anti-NXP-2 (P140) Ab (RDL) Units 82425-0
520080 MyoMarker 3 Profile (RDL) 520228 Anti-PM/Scl-100 Ab (RDL) Units 31562-2
520080 MyoMarker 3 Profile (RDL) 520031 Anti-Ku Ab (RDL) 18484-6
520080 MyoMarker 3 Profile (RDL) 520253 Anti-SS-A 52kD Ab, IgG (RDL) Units 70257-1
520080 MyoMarker 3 Profile (RDL) 520217 Anti-U1 RNP Ab (RDL) Units 57662-9
520080 MyoMarker 3 Profile (RDL) 520025 Anti-U2 RNP Ab (RDL) 68549-5
520080 MyoMarker 3 Profile (RDL) 520020 Anti-U3 RNP (Fibrillarin)(RDL) 49963-2

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