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Autoimmune Encephalitis Profile, Serum

CPT: 86255(x6)
Updated on 04/7/2021

Expected Turnaround Time

2 - 5 days

Related Documents

Specimen Requirements




2 mL

Minimum Volume

1 mL (Note: this volume does not allow for repeat testing.)


Serum from a red-top tube, gel-barrier tube, serum transfer tube

Serum from red-top tube

Serum from a red-top tube, gel-barrier tube, serum transfer tube

Storage Instructions

Room temperature

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Gross hemolysis, grossly lipemic, gross icetrus

Test Details


Evaluation of Autoimmune Encephalitis Antibody with Reflex to Titer


Negative results do not exclude autoimmune encephalopathy or cancer.

This test does not detect Ma1 or Ma2 antibodies (alias Mata), which are sometimes associated with brainstem and limbic encephalitis in context of testicular germ cell neoplasms.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.


Cell-based Immunofluorescence (IFA)

Additional Information

The Encephalitis Antibody Panel provides an evaluation of possible autoantibodies in patients with suspected autoimmune encephalitis, and optimizes the liklihood of detecting neuronal specific autoantibodies, whether present singly or occurring as multiple autoantibodies.

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