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Autoimmune Encephalitis Profile, Serum

CPT: 86255(x6)
86255(x6)86255(x6)
86255(x6)86255(x6)
Updated on 04/7/2021

Expected Turnaround Time

2 - 5 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

2 mL


Minimum Volume

1 mL (Note: this volume does not allow for repeat testing.)


Container

Serum from a red-top tube, gel-barrier tube, serum transfer tube

Serum from red-top tube

Serum from a red-top tube, gel-barrier tube, serum transfer tube


Storage Instructions

Room temperature


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Gross hemolysis, grossly lipemic, gross icetrus


Test Details


Use

Evaluation of Autoimmune Encephalitis Antibody with Reflex to Titer


Limitations

Negative results do not exclude autoimmune encephalopathy or cancer.

This test does not detect Ma1 or Ma2 antibodies (alias Mata), which are sometimes associated with brainstem and limbic encephalitis in context of testicular germ cell neoplasms.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.


Methodology

Cell-based Immunofluorescence (IFA)


Additional Information

The Encephalitis Antibody Panel provides an evaluation of possible autoantibodies in patients with suspected autoimmune encephalitis, and optimizes the liklihood of detecting neuronal specific autoantibodies, whether present singly or occurring as multiple autoantibodies.


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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf