LabCorp and its Specialty Testing Group, a fully integrated portfolio of specialty and esoteric testing laboratories.
5 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
1 mL (Note: This volume does not allow for repeat testing.)
Red-top tube or gel-barrier tube
Allow a minimum clotting time of 30 to 60 minutes with serum separation within 2 hours of collection. Send serum in a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Frozen (preferred) or refrigerated
Provides infliximab drug concentration levels as well as levels of anti-infliximab antibodies.
Failure of infliximab therapy may not always be due to the presence of anti-infliximab antibodies. In addition, the absence of anti-infliximab antibodies does not guarantee positive response to treatment.
Electrochemiluminescence immunoassay (ECLIA)
Infliximab drug level:
• Result ≥0.4 µg/mL indicates detection of infliximab.
• In the presence of anti-infliximab antibodies, the infliximab drug level reflects the antibody-unbound fraction of infliximab concentration in serum.
• Result ≥22 ng/mL indicates detection of anti-infliximab antibodies.
In the absence of anti-infliximab antibodies, the infliximab drug level typically reflects the total infliximab concentration in serum. In the presence of anti-infliximab antibodies, the infliximab drug level typically reflects the antibody-unbound fraction of infliximab concentration in serum. The presence of infliximab drug, even at concentrations well above target treatment levels (>50 μg/mL), does not interfere with the anti-infliximab antibody detection. This assay may be helpful for any patients on infliximab therapy for diseases such as Crohn's disease, inflammatory bowel disease, ulcerative colitis, rheumatoid arthritis, or other autoimmune conditions.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|503770||Infliximab (IFX) Conc+ IFX Ab||503772||Infliximab Drug Level||ug/mL||39803-2|
|503770||Infliximab (IFX) Conc+ IFX Ab||503773||Anti-Infliximab Antibody||ng/mL||72623-2|
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