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Hepatitis Profile IV (Hepatitis A and B Immune Status)

CPT: 86704; 86706; 86708; 86709
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  • HAV/HBV Immune Status (Profile IV)

Test Includes

Anti-HAV, total; anti-HAV, IgM (if anti-HAV, total is positive); anti-HBc; anti-HBs

Special Instructions

This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.

Expected Turnaround Time

1 - 2 days

Specimen Requirements


Serum or plasma


3 mL

Minimum Volume

2 mL (Note: This volume does not allow for repeat testing.)


Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube


If tube other than a gel-barrier tube is used, transfer separated serum or plasma to a plastic transport tube.

Storage Instructions

Room temperature

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Non-EDTA plasma specimen; PST gel-barrier tube

Test Details


See individual tests.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
058537 HAV/HBV Immune Status (Pro IV) 006734 Hep A Ab, IgM 13950-1
058537 HAV/HBV Immune Status (Pro IV) 006726 Hep A Ab, Total 13951-9
058537 HAV/HBV Immune Status (Pro IV) 006718 Hep B Core Ab, Tot 13952-7
058537 HAV/HBV Immune Status (Pro IV) 006408 Hep B Surface Ab, Qual 22322-2

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at Additional information regarding LOINC® codes can be found at, including the LOINC Manual, which can be downloaded at