Bilirubin, Total and Direct

CPT: 82247; 82248
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Synonyms

  • Bilirubin, Total, Conjugated, and Unconjugated

Test Includes

Bilirubin, conjugated (direct); bilirubin, indirect; bilirubin, total


Expected Turnaround Time

Within 1 day


Related Documents


Specimen Requirements


Specimen

Serum (preferred) or plasma


Volume

3 mL


Minimum Volume

1 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube


Collection

Separate serum or plasma from cells within 45 minutes of collection.


Storage Instructions

Refrigerate


Stability Requirements

Temperature

Period

Room temperature

2 days

Refrigerated

3 days

Frozen

14 days

Freeze/thaw cycles

Stable x2


Causes for Rejection

Severe hemolysis; improper labeling; severe lipemia


Test Details


Use

Liver and biliary tests are useful in the differential diagnosis of jaundice from bilirubin overproduction (hemolysis), decreased uptake (Gilbert disease), decreased conjugation (hepatocellular disease, familial, drug-induced, pregnancy; obstructive bile duct disease).


Methodology

Colorimetric


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
001214 Bilirubin, Total/Direct, Serum 34543-9 001099 Bilirubin, Total mg/dL 1975-2
001214 Bilirubin, Total/Direct, Serum 34543-9 001222 Bilirubin, Direct mg/dL 1968-7
001214 Bilirubin, Total/Direct, Serum 34543-9 011247 Bilirubin, Indirect mg/dL 1971-1

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