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Red Blood Cell (RBC) Antigen Typing: k (Cellano)
Typing paternal RBCs for antigens that correspond to maternal antibody may aid in the prediction of hemolytic disease of the fetus and newborn. Red cell antigen typing may also be indicated for bone marrow, tissue, organ, or blood donors prior to donation. Testing a prenatal patient for red cell antigens is generally not indicated. The occurrence of the little k antigen is 99.8% in Caucasians and 100% in Blacks. Anti-K can cause mild to severe (rare) hemolytic disease of the fetus and newborn.
Presence of potent cold agglutinins, positive direct antiglobulin test, and (in some cases) bacteremia may interfere with test interpretation.
Causes for Rejection
Gross hemolysis; bacterial or other contamination
This test does not include big K (Kell). To order big K typing, refer to test 006068.