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Adalimumab Concentration and Anti-Adalimumab Antibody
- Anti-TNF-alpha Drug
Monitor anti-adalimumab therapy for individuals with Crohn's disease, inflammatory bowel disease, ulcerative colitis, rheumatoid arthritis, or other autoimmune conditions. This test provides adalimumab drug concentration levels as well as the level of anti-adalimumab antibodies.
In the absence of anti-adalimumab antibodies, the adalimumab drug level typically reflects the total adalimumab concentration in serum. In the presence if anti-adalimumab antibodies, the adalimumab level typically reflects the antibody-unbound fraction of adalimumab concentration in serum.
This assay provides clinically valid antibody results at drug levels well above treatment targets (>30 ug/mL). Failure of adalimumab therapy may not always be due to the presence of anti-adalimumab antibodies. In addition, the absence of anti-adalimumab antibodies does not guarantee positive response to treatment.
Electrochemiluminescence Immunoassay (ECLIA)
1 mL (Note: This volume does not allow for repeat testing).
Red-top tube or gel-barrier tube
Serum must be separated from cells within 45 minutes of venipuncture. Send serum in a plastic transport tube. To avoid delays in turnaround time when requesting multiple test on frozen samples, please submit separate frozen specimens for each test requested.
Refrigerate or freeze
Causes for Rejection
Plasma specimen received
This test is pending NY state approval.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|504575||Adalimumab+Ab||503866||Adalimumab Drug Level||ug/mL||74117-3|