Microarray-Products of Conception (POC) Reveal® FFPE

CPT: 81229
Print Share

Test Details


  • aCGH
  • CGH
  • CMA
  • Microarray
  • Reveal® SNP Microarray-Products of Conception (POC)
  • SNP Array
  • WGA


Detects chromosomal imbalance that may be associated with fetal loss and is ideal for detection of complete or partial molar pregnancies.

The microarray will detect DNA copy-number changes at a threshold >1Mb for deletions, >2 Mb for duplications. Also will detect copy-neutral changes associated with uniparental disomy and identity by descent.


This assay does not detect balanced rearrangements and low level mosaicism, or tetraploidy.

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Whole genome SNP copy number microarray analysis using Molecular Inversion Probe (MIP) technology optimized for highly degraded FFPE samples.

Specimen Requirements


Preferred fixed products of conception (POC), formalin-fixed paraffin-embedded (FFPE) tissue


One paraffin block or ten 10-micron thick section slides

Minimum Volume

Sufficient sample to obtain enough DNA to run microarray


Paraffin block transport pouch


Specimen should be fixed in 10% neutral-buffered formalin or formaldehyde.

Storage Instructions

Room temperature

Causes for Rejection

Improperly embedded preparation

Clinical Information

Special Instructions

Pertinent medical findings should accompany the test request form. Please direct questions to genetic customer service at 800-345-4363.

This assay is not approved for patients of New York State physicians.


Wang Y, Cheng Q, Meng L, et al. Clinical application of SNP array analysis in first-trimester pregnancy loss: a prospective study. Clin Genet. 2017 Jun;91(6):849-858.27883173


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
511997 Reveal(R) POC Paraffin 511998 Specimen Type 31208-2
511997 Reveal(R) POC Paraffin 511999 # of Genotyping Targets N/A
511997 Reveal(R) POC Paraffin 512000 Array Type N/A
511997 Reveal(R) POC Paraffin 512001 Diagnosis 48000-4
511997 Reveal(R) POC Paraffin 512002 Interpretation 62365-2
511997 Reveal(R) POC Paraffin 512003 Director Review 48672-0
511997 Reveal(R) POC Paraffin 512123 PDF 80563-0

For Providers

Please login to order a test.


© 2018  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf