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Microarray-Products of Conception (POC) Reveal® FFPE
- Reveal® SNP Microarray-Products of Conception (POC)
- SNP Array
Detects chromosomal imbalance that may be associated with fetal loss and is ideal for detection of complete or partial molar pregnancies.
The microarray will detect DNA copy-number changes at a threshold >1Mb for deletions, >2 Mb for duplications. Also will detect copy-neutral changes associated with uniparental disomy and identity by descent.
This assay does not detect balanced rearrangements and low level mosaicism, or tetraploidy.
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).
Whole genome SNP copy number microarray analysis using Molecular Inversion Probe (MIP) technology optimized for highly degraded FFPE samples.
Preferred fixed products of conception (POC), formalin-fixed paraffin-embedded (FFPE) tissue
One paraffin block or ten 10-micron thick section slides
Sufficient sample to obtain enough DNA to run microarray
Specimen should be fixed in 10% neutral-buffered formalin or formaldehyde.
Causes for Rejection
Improperly embedded preparation
Pertinent medical findings should accompany the test request form. Please direct questions to genetic customer service at 800-345-4363.
This assay is not approved for patients of New York State physicians.