Parentage/Relationship Testing

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Test Details

Synonyms

  • DNA Analysis for Parentage Evaluation
  • Exclusion of Parentage
  • Genetic testing for parentage Evaluation
  • Grandparent Studies
  • Immigration Testing
  • Parentage Studies
  • Paternity Testing
  • Relationship testing
  • Sibling determination
  • STR Analysis

Use

Determine the chance of paternity or nonpaternity in cases of disputed paternity, establish blood relationship of potential immigrant, sibling determination, grandparent/child testing, other relationships

Limitations

Probability of parentage is provided for nonexcluded individuals, which is a probability, not a “yes” answer. Some tests may be inconclusive. Mutations, related alleged fathers, and other genetic limitations may affect the test.

Methodology

DNA analysis by polymerase chain reaction (PCR)

Specimen Requirements

Storage Instructions

Maintain specimen at room temperature and keep dry.

Causes for Rejection

Inadequate labeling; improperly filled-out client authorization/chain-of-custody form; insufficient amount of DNA on buccal swabs

Clinical Information

Special Instructions

Appointments and paternity kits are required. Specimens must be collected with chain-of-custody paperwork. Clinical account numbers cannot be used. To receive a complete paternity kit, blood or buccal swab, set up account numbers, or for an appointment, telephone 800-742-3944.

References

Brooks MA. Paternity testing. In Harmening D, ed. Modern Blood Banking and Transfusion Practices. 2nd ed. Philadelphia, Pa:FA Davis Co;1989:379-389.
Bryant NJ. Paternity testing: Current status and review. Transfus Med Rev. 1988 Mar;2(1):29-39.2908780
Guidelines for reporting estimates of probability of paternity. Council on Scientific Affairs. JAMA. 1985 Jun 14;253(22):3298.3999317

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf