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Golimumab and Anti-Golimumab Antibody
Failure of golimumab therapy may not always be due to the presence of anti-golimumab antibodies. Conversely, the absence of anti-golimumab antibodies does not guarantee response to treatment.
Golimumab drug level: <0.5 μg/mL
• Result ≥0.5 μg/mL indicates detection of golimumab
• In the presence of serum anti-golimumab antibodies, the golimumab drug level reflects the antibody-unbound (free) fraction of golimumab in serum.
Anti-golimumab antibody: <20 ng/mL
• Result ≥20ng/mL indicates detection of anti-golimumab antibodies.
Serum or plasma (EDTA)
Serum/plasma must be separated from cells within 45 minutes of venipuncture. Send serum/plasma in a plastic transport tube. To avoid delays in turnaround time when requesting multiple test on frozen samples, please submit seperate frozen specimens for each test requested.
Causes for Rejection
Gross hemolysis, gross lipemia
This test is pending NY state approval.