Sulfonylurea Analysis, Serum or Plasma

CPT: 80377
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Test Includes

Acetohexamide; chlorpropamide; glimepiride; glipizide; glyburide; nateglinide; repaglinide; tolazamide; tolbutamide

Expected Turnaround Time

10 - 14 days

Specimen Requirements


Serum or plasma


2 mL

Minimum Volume

1 mL


Red-top tubeor green-top (heparin) tube. Gel-barrier tubes are not recommended.


Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.

Causes for Rejection

Gel-barrier tubes

Test Details


Detect the presence of sulfonylurea class drugs


Liquid chromatography/tandem mass spectrometry (LC/MS-MS)


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
814133 Sulfonylurea Screen, QT 814134 Acetohexamide ug/mL 27007-4
814133 Sulfonylurea Screen, QT 814135 Chlorpropamide ug/mL 3474-4
814133 Sulfonylurea Screen, QT 814136 Tolazamide ug/mL 9629-7
814133 Sulfonylurea Screen, QT 815298 Tolbutamide ug/mL 4061-8
814133 Sulfonylurea Screen, QT 815299 Glimepiride ng/mL 40465-7
814133 Sulfonylurea Screen, QT 815300 Glipizide ng/mL 10539-5
814133 Sulfonylurea Screen, QT 815301 Glyburide ng/mL 10540-3
814133 Sulfonylurea Screen, QT 815302 Nateglinide ng/mL 49702-4
814133 Sulfonylurea Screen, QT 815303 Repaglinide ng/mL 38542-7

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