Ephedrine/Pseudoephedrine Differentiation, Serum or Plasma

CPT: 80324
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Test Details


  • White Cross

Test Includes

Ephedrine; pseudoephedrine


Detect, quantitate, and differentiate between the stereoisomers ephedrine and pseudoephedrine.


Gas chromatography/electron capture detection (GC/EC)

Reference Interval

Ephedrine: 35−80 ng/mL; pseudoephedrine: 200−800 ng/mL

Specimen Requirements


Serum or plasma, protected from light


3 mL

Minimum Volume

0.6 mL


Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Patient Preparation

Trough levels are most reproducible.


Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube. Wrap specimen in foil to protect from light.

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen. Protect from light.

Causes for Rejection

Gel-barrier tubes; specimen not light-protected


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
808162 Ephedrine/Pseudoephedrine 808163 Ephedrine ng/ml 3591-5
808162 Ephedrine/Pseudoephedrine 808164 Pseudoephedrine ng/ml 9389-8

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