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Therapeutic drug management; detect presence of dextromethorphan, an over-the-counter cough suppressant with abuse potential
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Serum or plasma
Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.
Trough levels are most reproducible.
Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen. Specimen is stable three days at room temperature; two weeks refrigerated or frozen.
Causes for Rejection
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