Carbamazepine and Carbamazepine-10,11 Epoxide, Serum or Plasma

CPT: 80156; 80161
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Synonyms

  • Carbatrol®
  • Epitol®
  • Tegretol®

Expected Turnaround Time

3 - 5 days


Specimen Requirements


Specimen

Serum or plasma


Volume

2 mL


Minimum Volume

0.5 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.


Collection

Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.


Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.


Patient Preparation

Trough levels are most reproducible.


Causes for Rejection

Gel-barrier tubes


Test Details


Use

Therapeutic drug management


Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)


Reference Interval

Carbamazepine: 4.0−12.0 µg/mL; carbamazepine-10,11-epoxide: 0.4−4.0 µg/mL


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
803189 Carbamazepine + Carb Epoxide 808278 Carabamazepine ug/ml 3432-2
803189 Carbamazepine + Carb Epoxide 808279 Carbamazepine-10,11-Epoxide ug/ml 9415-1

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