Atomoxetine, Serum or Plasma

CPT: 80375
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Test Details

Synonyms

  • Strattera®

Use

Therapeutic drug management

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Reference Interval

Therapeutic range has not been established. Poor metabolizers of cytochrome P450 2D6 (CYP2D6) substrates may have steady-state atomoxetine concentrations sixfold greater than those of extensive metabolizers.

Specimen Requirements

Specimen

Serum or plasma

Volume

2 mL

Minimum Volume

0.5 mL

Container

Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Patient Preparation

Trough levels are most reproducible.

Collection

Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen. Specimen is stable for three days at room temperature, for seven days refrigerated, and for six months frozen.

Causes for Rejection

Gel-barrier tubes

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
790640 Atomoxetine (Strattera), Serum 35667-5 790581 Atomoxetine ng/ml 35667-5
790640 Atomoxetine (Strattera), Serum 35667-5 790579 Atomoxetine, Serum N/A

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The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf