Amoxapine and 8-Hydroxyamoxapine, Serum or Plasma

CPT: 80335
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Test Details


  • Asendin®


Therapeutic drug management


High-pressure liquid chromatography with ultraviolet detection (HPLC/UV)

Reference Interval

Combined total of amoxapine and 8-hydroxyamoxapine: 200−400 ng/mL.

Specimen Requirements


Serum or plasma


2 mL

Minimum Volume

0.5 mL


Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Patient Preparation

Trough levels are most reproducible.


Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.

Causes for Rejection

Gel-barrier tubes


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
808188 Amoxapine (Asendin) 808192 Amoxapine ng/ml 3341-5
808188 Amoxapine (Asendin) 808193 8-Hydroxy-Amoxapine ng/ml 1698-0
808188 Amoxapine (Asendin) 808194 Combined Total ng/ml 9625-5
808188 Amoxapine (Asendin) 808195 Amoxapine (Asendin) N/A

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