Amantadine, Serum or Plasma

CPT: 80299
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Synonyms

  • Symmetrel®

Expected Turnaround Time

10 - 14 days


Specimen Requirements


Specimen

Serum or plasma


Volume

3 mL


Minimum Volume

1.2 mL


Container

Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.


Collection

Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.


Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.


Patient Preparation

Trough levels are most reproducible.


Causes for Rejection

Gel-barrier tubes


Test Details


Use

Therapeutic drug management


Methodology

Liquid chromatography/tandem mass spectrometry (LC-MS/MS)


Reference Interval

Therapeutic range has not been established. Expected steady-state amantadine concentrations in patients receiving recommended daily dosages: 200−1000 ng/mL.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
808399 Amantadine (Symmetrel) 3317-5 808400 Amantadine ng/ml 3317-5

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