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Therapeutic drug management
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
5−25 ng/mL. Note: Some patients respond well to high-dose alprazolam therapy with resultant serum concentrations 25−55 ng/mL.
Serum or plasma
Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.
Trough levels are most reproducible.
Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen. Specimen is stable for eight days at room temperature or refrigerated, and for 19 days frozen.
Causes for Rejection
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|842039||Alprazolam (Xanax)||3312-6||808489||Alprazolam (Xanax)||ng/mL||3312-6|