PD-L1, IHC (Atezolizumab), Non-Small-cell Lung Cancer

CPT: 88360
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Test Details


  • Programmed Death Ligand 1
  • Tecentriq™


The PD-L1 (SP142) is a qualitative IHC assay intended for use in the detection of PD-L1 in formalin-fixed, paraffin embedded (FFPE) in non-small-cell lung cancer tissue samples using the Ventana BenchMark Ultra Platform.


Immunohistochemistry using Ventana BenchMark Ultra.

Specimen Requirements


Formalin-fixed, paraffin-embedded (FFPE) tissue block or slides


At least two unstained slides sectioned at 4 microns, less than two months of sectioning if stored at 15°C to 30°C. Four slides are ideal.

Minimum Volume

Two unstained slides at 4 microns, less than two months of sectioning if stored at 15°C to 30°C.


Paraffin block or unstained positive charged slides


Paraffin block or unstained slides sectioned if stored at 15°C to 30°C for two months age.

Storage Instructions


Causes for Rejection

Slides sectioned more than two months prior to test request and not stored at 15°C to 30°C

Clinical Information

Special Instructions

PD-L1 testing will be delayed if the pathology report is not received.

Note: This test number is used for tracking oncology IHC specimens to the laboratory. Bill codes will be added when testing is complete, based on the processes performed in the laboratory.


Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med. 1999; (12):1365-1369.10581077
Ventana, 1016217US Rev A [package insert] Ventana.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
451949 PD-L1 IHC, TECENTRIQ (TM)Lung 85149-3 451944 Result 83057-0
451949 PD-L1 IHC, TECENTRIQ (TM)Lung 85149-3 451945 % Tumor Cells Staining: % 83053-9
451949 PD-L1 IHC, TECENTRIQ (TM)Lung 85149-3 451946 Comment 77202-0
451949 PD-L1 IHC, TECENTRIQ (TM)Lung 85149-3 451947 Interpretation 77202-0
451949 PD-L1 IHC, TECENTRIQ (TM)Lung 85149-3 451948 Director Review 72486-4

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