Respiratory Pathogen Profile, PCR

CPT: 87633; 87486; 87581; 87798
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Test Details

Test Includes

Adenovirus; Bordetella pertussis; Chlamydophila pneumoniae; coronavirus 229E; coronavirus HKU1; coronavirus NL63; coronavirus OC43; human metapneumovirus; human rhinovirus/enterovirus; influenza A; influenza A subtype H1; influenza A subtype H3; influenza A subtype H1-2009; influenza B; Mycoplasma pneumoniae; parainfluenza virus 1; parainfluenza virus 2; parainfluenza virus 3; parainfluenza virus 4; respiratory syncytial virus

Use

This test provides simultaneous qualitative detection and identification of multiple respiratory viral and bacterial nucleic acids in nasopharyngeal swabs obtained from individuals suspected of respiratory tract infections.

Limitations

The performance of this test has not been established for patients without signs and symptoms of respiratory infection. Results from this test must be correlated with the clinical history, epidemiological data, and other data available to the clinician evaluating the patient. Viral and bacterial nucleic acids may persist in vivo independent of organism viability. Detection of organism target(s) does not imply that the corresponding organisms are infectious or are the causative agents for clinical symptoms. The detection of viral and bacterial nucleic acid is dependent upon proper specimen collection, handling, transportation, storage and preparation. Failure to observe proper procedures in any one of these steps can lead to incorrect results. There is a risk of false positive or false negative values resulting from improperly collected, transported or handled specimens.

Methodology

Polymerase chain reaction (PCR)

Specimen Requirements

Specimen

Nasopharyngeal swab

Volume

One swab in viral transport

Minimum Volume

0.3 mL

Container

Viral Transport System

Storage Instructions

Freeze. Per the package insert: Swabs in viral transport media are stable for 30 days at -15°C or below. Swabs in viral transport media are also stable for 4 hours at room temperature and 3 days refrigerated (2º to 8º C).

Causes for Rejection

Improper collection; inadequate specimen; improper labeling; specimen leaked in transit; quantity not sufficient for analysis; name discrepancies; specimen exceeding storage requirements; specimen types other than nasopharyngeal swab in viral transport media

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
139650 Respiratory Profile, PCR 82159-5 139592 Adenovirus 82160-3
139650 Respiratory Profile, PCR 82159-5 139593 Coronavirus HKU1 82161-1
139650 Respiratory Profile, PCR 82159-5 139594 Coronavirus NL63 82162-9
139650 Respiratory Profile, PCR 82159-5 139597 Coronavirus 229E 82163-7
139650 Respiratory Profile, PCR 82159-5 139601 Coronavirus OC43 82164-5
139650 Respiratory Profile, PCR 82159-5 139602 Human Metapneumovirus 82165-2
139650 Respiratory Profile, PCR 82159-5 139604 Human Rhinovirus/Enterovirus 82175-1
139650 Respiratory Profile, PCR 82159-5 139606 Influenza A 82166-0
139650 Respiratory Profile, PCR 82159-5 139611 Influenza A/H1 82167-8
139650 Respiratory Profile, PCR 82159-5 139612 Influenza A/H1-2009 82168-6
139650 Respiratory Profile, PCR 82159-5 139613 Influenza A/H3 82169-4
139650 Respiratory Profile, PCR 82159-5 139614 Influenza B 82170-2
139650 Respiratory Profile, PCR 82159-5 139651 Parainfluenza 1 82171-0
139650 Respiratory Profile, PCR 82159-5 139652 Parainfluenza 2 82172-8
139650 Respiratory Profile, PCR 82159-5 139653 Parainfluenza 3 82173-6
139650 Respiratory Profile, PCR 82159-5 139654 Parainfluenza 4 82174-4
139650 Respiratory Profile, PCR 82159-5 139656 Respiratory Syncytial Virus 82176-9
139650 Respiratory Profile, PCR 82159-5 139657 Bordetella pertussis 82179-3
139650 Respiratory Profile, PCR 82159-5 139658 Chlamydophila pneumoniae 82178-5
139650 Respiratory Profile, PCR 82159-5 139659 Mycoplasma pneumoniae 82177-7

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf