PD-L1, IHC (Atezolizumab), Urothelial Cancer

CPT: 88360
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Test Details


  • Programmed Death Ligand 1
  • Tecentriq™


The PD-L1 (SP142) is a qualitative assay intended for use in the detection of PD-L1 in formalin-fixed, paraffin-embedded (FFPE) urothelial cancer tissue samples.


Immunohistochemistry (IHC), Ventana BenchMark Ultra platform

Specimen Requirements


Formalin-fixed, paraffin-embedded (FFPE) tissue block or slides


At least two unstained slides sectioned at 4 microns, less than two months since sectioning if stored at 15°C to 30°C. Four slides are ideal.

Minimum Volume

Two unstained slides at 4 microns less than two months since sectioning if stored at 15°C to 30°C.


Paraffin block or unstained positively-charged slides


Paraffin block or unstained slides sectioned if stored at 15°C to 30°C for two months

Storage Instructions


Causes for Rejection

Slides sectioned greater than two months prior to test request and not stored at 15°C to 30°C

Clinical Information

Special Instructions

PD-L1 testing will be delayed if the pathology report is not received.

Note: This test number is used for tracking oncology IHC specimens to the laboratory. Bill codes will be added when testing is complete, based on the processes performed in the laboratory.


Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med. 1999 Dec; 5(12):1365-1369. 10581077
Ventana 790-4859, 1014003EN Rev A [package insert] Ventana; 1-4.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
451909 PD-L1 IHC, TECENTRIQ (TM) 85149-3 451921 Result 83057-0
451909 PD-L1 IHC, TECENTRIQ (TM) 85149-3 451922 % Tumor Cells Staining: % 83053-9
451909 PD-L1 IHC, TECENTRIQ (TM) 85149-3 451923 Comment 77202-0
451909 PD-L1 IHC, TECENTRIQ (TM) 85149-3 451924 Interpretation 77202-0
451909 PD-L1 IHC, TECENTRIQ (TM) 85149-3 451925 Director Review 72486-4

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